2001-2008
West’s sound was featured heavily on Jay-Z's critically-acclaimed album The Blueprint, released on September 11, 2001. His work was featured on the lead single "Izzo (H.O.V.A.)" and a diss track against Nas and Mobb Deep named "Takeover"; West has worked with Mobb Deep and Nas since the track's release. West soon became a major name in hip hop production following the release of the album, but struggled to find a way to get a record deal. Jay-Z admitted that Roc-A-Fella was initially reluctant to support West as a rapper, claiming that he saw him as a producer first and foremost. Multiple record companies pushed him aside because he was not the stereotypical hip hop artist. Companies felt he was not as marketable as rappers that portray the "street image" that is prominent in hip hop culture.

On October 23, 2002, West was involved in a near fatal car crash while driving home from the recording studio. The crash provided inspiration for West's first single, "Through the Wire". West's faith is apparent in many of his songs, such as "Jesus Walks", which became a staple at his benefit performances, such as the Live 8 concert. These songs were featured on West's debut album, The College Dropout, which was released on Roc-A-Fella Records in February 2004, and went on to receive critical acclaim. The album also defined the style for which West would become known, including wordplay and sampling. The album went certified triple platinum. Guest appearances included Jay-Z, Ludacris, GLC, Consequence, Talib Kweli, Common, and Syleena Johnson. The album also featured the singles, "All Falls Down" and "The New Workout Plan", as well as Twista's single, "Slow Jamz".

West was involved in a financial dispute over Royce Da 5'9"'s song "Heartbeat", produced by West and released on Build & Destroy: The Lost Sessions. West maintains that Royce never paid for the beat, but recorded to it and released it; hearing him on the beat, the original customers decided not to buy it from West. After the disagreement, West vowed to never work with Royce again. Other Kanye West-produced hit singles during the period The College Dropout was released included "I Changed My Mind" by Keyshia Cole, "Overnight Celebrity" by Twista and "Talk About Our Love" by Brandy.

On August 30, 2005, West released his second album Late Registration. Reviews were mostly favorable: "Late Registration is an undeniable triumph" (Rolling Stone), "As ornate and bloated as West's ego." (Spin September 2005, p.99). With the help of producer samples in different ways along with compositions of strings and other sounds. The record earned the number one spot on the Village Voice's Pazz & Jop critics poll of 2005. The first two singles from Late Registration were "Diamonds from Sierra Leone" (which features vocals from Shirley Bassey's "Diamonds Are Forever") and "Gold Digger" featuring Jamie Foxx (which contains an interpolation of Ray Charles's "I Got a Woman") to sell over 860,000 copies in its first week, and earned him eight Grammy Award nominations including Album of the Year and Record of the Year for the song "Gold Digger". The album also included "My Way Home", a track that sampled Gil Scott-Heron's mournful "Home Is Where The Hatred Is". The album is certified triple platinum. Guest appearances include Jamie Foxx, Adam Levine, Paul Wall, GLC, Cam'ron, Common, Brandy, Jay-Z, Consequence, The Game & Really Doe.

In January 2006, West again sparked controversy when he appeared on the cover of Rolling Stone in the image of Jesus wearing a crown of thorns. Later that month, he suggested in Playboy that if a Bible were written in the present day, he is famous and important enough to be included in it. "I throw up historical subjects in a way that makes kids want to learn about them," West claimed, "[I'm] definitely in the history books already."

After the 2006 Grammy nominations were released, West said he would "really have a problem" if he didn't win the Album of the Year because of the comments, saying "I don't care what I do, I don't care how much I stunt — you can never take away from the amount of work I put into it. I don't want to hear all of that politically correct stuff." West won several Grammy awards, including Best Rap Album, but did not win the Album of the Year Award. The award instead went to U2's How to Dismantle an Atomic Bomb. Coincidentally, in November 2006, West was the opening act for U2 during the fifth leg of their Vertigo Tour in Australia and New Zealand.

On August 5, 2006, West headlined the second day of the Lollapalooza music festival in his hometown of Chicago. Later that month, People magazine reported that West became engaged to his girlfriend Alexis while spending two weeks overseas with her.
On November 2, 2006, when "Touch the Sky" failed to win Best Video at the MTV Europe Music Awards, West went onto the stage as the award was being presented to Justice and Simian for "We Are Your Friends" and argued that he should have won the award instead. Hundreds of news outlets worldwide criticized the outburst. On November 7, 2006, West apologized for this outburst publicly during his performance as support act for U2 for their Vertigo concert in Brisbane, Australia.

In December 2006, Robert "Evel" Knievel sued West for trademark infringement in West's video for "Touch the Sky". Knievel is taking issue with a "sexually-charged video" in which West takes on the persona of "Evel Kanyevel" and attempts flying a rocket over a canyon. The suit filed in federal court claims infringement on his trademarked name and likeness. Knievel also claims the "vulgar and offensive" images depicted in the video damage his reputation. The suit seeks damages and to stop distribution of the video.

In 2007, it was announced that West would be starring in a series directed by Larry Charles. He has been working on the pilot episode for the past two years with Larry Charles and Rick Rubin. He also had this to say on January 14: "I wouldn't do something as cliché as a reality show. At least give me the credit for being more creative than that. It's a situational half-hour comedy. It's fictional, and loosely based on my life." West recently collaborated with Japanese hip hop group Teriyaki Boyz to produce the single "I Still Love H.E.R.", a reference to Common's 1994 single "I Used to Love H.E.R.". It is rumored that West's introductory lines preceding his verse are a thinly-veiled jab at producer and rapper Danny!, who was mercilessly compared to West in the beginning of his career.

Further to this, during a radio appearance in early 2007, West, like many of his peers, recorded an impromptu freestyle to the popular song "Throw Some D's". West's version became extremely popular because of the different stance he took. The song that to all other rappers was about automobile rims, was used by West to comically refer to D-cup breasts. Because of the unexpected success of the song, West went on to make a video for the freestyle, in which he is seen playing his 'Old Ass Cousin'.

West was also featured in a new song called "Classic (Better Than I've Ever Been)". It was believed to be a single from his upcoming album, Graduation, because he is featured on the track, but Nike quickly explained that it was for the Nike Air Force 1's anniversary. It was meant only to be an exclusive track for the company.
In July 2007, West changed the release date of Graduation, his third album, from September 18, 2007, to the same release date as 50 Cent's album Curtis, September 11, 2007. 50 Cent later claimed that if Graduation were to sell more records than Curtis, he would stop releasing solo albums. However, 50 Cent would later dispel his comments. The album has been certified double platinum. Guest appearances included T-Pain, Mos Def, & Lil Wayne.

Like its predecessors, West's Graduation contained extensive sampling of music by eclectic and often obscure artists, including "Champion", taking its hook from a snippet of Steely Dan's "Kid Charlemagne", and "The Glory", which uses as its foundation Laura Nyro's "Save the Country". On August 26, 2007, West appeared as himself on the HBO television show Entourage which he used as a platform to premier his new single "Good Life" during the end credits. In September 2007, West suggested that his race had to do with his being overlooked for opening the MTV Video Music Awards in favor of Britney Spears; he claimed, "Maybe my skin’s not right." On September 9, 2007, West performed at the 2007 MTV Video Music Awards. On that night, he lost all 5 awards that he was nominated for, including Best Male Artist and Video of the Year. After the show, he was visibly upset that he had lost at the VMA's 2 years in a row, stating that he would not come back to MTV ever again. He also appeared on several radio stations saying that when he made the song "Stronger" that it was his dream to open the VMA's with it. He has also stated that Britney Spears hasn't had a hit in a long period of time and that MTV exploited her for ratings. Kanye West was nominated in 8 Grammy Award categories for the 50th annual Grammy Awards.

HURRICANE KATRINA FUNDRAISER CONTROVERSY
On September 2, 2005, during a benefit concert for Hurricane Katrina relief on NBC, A Concert for Hurricane Relief, West was a featured speaker. Controversy arose when West was presenting, as he deviated from the prepared script:
"I hate the way they portray us in the media. You see a black family, it [the media] says, 'they're looting'. You see a white family, it says, 'they're looking for food'. And, you know, it's been five days [waiting for federal help] because most of the people are black. And even for me to complain about it, I would be a hypocrite because I've tried to turn away from the TV, because it's too hard to watch. I've even been shopping before even giving a donation, so now I'm calling my business manager right now to see what's, what is the biggest amount I can give, and just to imagine if I was, if I was down there, and those are, those are my people down there. So anybody out there that wants to do anything that we can help — with the set up, the way America is set up to help, the poor, the black people, the less well-off, as slow as possible. I mean, this is, the Red Cross is doing everything they can. We already realize a lot of people that could help are at war right now, fighting another way — and they've given them permission to go down and shoot us!"